HIV Bone Marrow Cure to Remove the Virus Permanently

By on September 3, 2013

A bone marrow transplant is also known as a stem cell transplant, is a procedure help to replace damaged and destroyed bone marrow with healthy bone marrow stem cells.

Stem cells in bone marrow develop three important types of blood cells like white blood cells, red blood cells and platelets.

HIV bone marrow cure involves taking healthy stem cells from the bone marrow of one person and transferring them to the bone marrow of another person.

Options of bone marrow stem cells:

HIV Bone Marrow Cure

  • Bone marrow harvest: Gathering stem cells directly from the bone.
  • Umbilical cord blood: Collecting stem cells from the blood in the umbilical cord after the baby birth.
  • Apheresis: Collecting stem cells by filtering the blood for peripheral blood cells (PBSC).

In most of cases, HIV bone marrow cure done by apheresis because this procedure provides much better results for both the donor and the recipient.

Bone marrow transplant procedure:

Bone marrow transplant is generally performed in medical centers that are specialized in such kind of treatments. HIV bone marrow cure involves five stages such as:

  • A physical examination and medical history that help to evaluate a person’s overall health condition.
  • Finding the options of the bone marrow stem cells.
  • Preparing the body for bone marrow transplant.
  • For the stem cell collection, the donor is connected to a device with a needle inserted in the vein. Blood is taken from the vein and filter by the machine to collect the stem cells.
  • It will be a one-time treatment by which stem cells express HIV-resistant genes, which often produce an entire HIV-resistant immune system.

HIV [How HIV Affects Our Body] positive patients who had bone marrow transplants have cured without taking HIV medications and there is no sign of the virus returning. In bone marrow transplant, stem cells are replaced by the healthy cells from the donor, and there is no HIV virus will exist after the treatment.

After completion of the treatment, again the patient needs to undergo the HIV test to determine the existence of the virus. Patient remains virus-free between three and four years after undergoing a bone marrow blood transplant.

There is no recovery period with this procedure. Many patients take up to a year to fully recover from the procedure. The result is very encouraging, but we need longer-term follow-up. But all HIV-positive people need to take antiretroviral drugs for life-long as the virus may hide in the body and re-emerge if treatment is halted.

HIV bone marrow cure as a way of treating the infected people is not a permanent cure for the disease. Also, bone morrow transplants are costly and risky. A patient may face 20% risk of death. Prior undergoing the procedure, the patient’s immune system needs to be weakened to reduce the risk of rejection.

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