Head and Neck Cancer Risk Reduced With Mood Stabilizing Drug

By on March 24, 2014

A new study has found out that the risk of head and neck cancer can be reduced with help of commonly used mood stabilizing drug.

Valproic acid is the drug, which commonly prescribed for mood stabilization, and also as an anti-seizure drug.

This drug contains histone acetyl transferases, due to which, this is drug is even studied as an anti-cancer drug.

Actually, histone acetyl transferases help in controlling gene expression by DNA structure alteration.

This study was lead by Johann Christoph Brandes MD, PhD. He is from Atlanta Veterans Affairs Medical Center and Emory University in Atlanta.

Head and Neck Cancer Risk - Valproic acidThe study was conducted on 439,628 veterans. Of these veterans, 26,911 were under the medication treatment for bipolar disorder, PTSD, seizures, and migraines.

It was found out that there was 34 percentages of reduced head and neck cancer development risk in veterans who were taking Valproic acid medication for at least a year when compared to veterans who were not taking such medication.

They also found that there were additional benefits of taking Valproic acid drug in higher dose and for longer period.

Dr. Johann Christoph Brandes said that with 34% head and neck cancer risk reduction means nearly 16000 fresh head and neck cancer cases can be prevented and nearly 3000 to 4000 deaths caused due this cancer annually can be prevented.

He also said that Valproic acid drug being a low cost medicine, and of low toxicity can show great impact on head and neck cancer treatment with respect cost, pain, and suffering.

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